Performance · Tier 1
Tesamorelin
FDA-approved for reducing deep abdominal fat.
Tesamorelin works like sermorelin but lasts longer in the body. It is the only peptide we offer that currently holds FDA approval, which gives it a level of evidence the others do not have.
- Format
- Subcutaneous injection
- Cadence
- Daily
- Typical course
- 3 to 6 months
- Tier
- Tier 1, $199 per vial
How it works
Longer lasting
It is built to resist being broken down quickly, so it stays active longer than sermorelin and produces a stronger effect.
Targets deep abdominal fat
Its approval studies showed it reduced visceral fat, the kind stored deep around your organs, rather than the fat just under the skin.
Keeps your natural rhythm
Like sermorelin, it prompts your own body to release growth hormone, so your natural controls stay in place.
What the evidence says
Tesamorelin is FDA-approved for a specific condition, with full clinical trials behind it. Using it for general body composition in adults without that condition is off-label. That is normal medical practice, but the approval does not carry across to that use.
What to expect
- Weeks 1 to 4
Settling in. Changes are not visible yet.
- Months 2 to 3
This is where measurable change appeared in the approval studies.
- Months 3 to 6
Full review with your physician, including bloodwork.
Protocol
| Standard | Daily injection |
|---|---|
| Timing | Bedtime, on an empty stomach |
| Monitoring | Bloodwork before starting, then at 12 and 24 weeks |
Blood sugar monitoring matters with this one, because growth hormone can affect how your body handles glucose.
Is it right for you?
Often a good fit
- Adults whose main concern is deep abdominal fat rather than overall weight
- People who want the option with the strongest evidence behind it
- People who did not get enough from sermorelin
Not a fit
- Pregnancy or breastfeeding
- Anyone with an active cancer diagnosis
- People with poorly controlled diabetes, without close monitoring
- Athletes in tested sport, where it is banned