Performance · Tier 1
Sermorelin
Studied for sleep quality, recovery and body composition.
Sermorelin prompts your body to release more of its own growth hormone rather than supplying growth hormone directly. That difference matters, because it leaves your body's natural controls in place.
- Format
- Subcutaneous injection
- Cadence
- Nightly at bedtime
- Typical course
- 3 to 6 months
- Tier
- Tier 1, $199 per vial
How it works
Prompts rather than replaces
Sermorelin signals the pituitary gland to release your own growth hormone in its natural rhythm, instead of flooding the system from outside.
Works with your sleep
Your largest natural release of growth hormone happens in deep sleep. Dosing at bedtime is designed to work with that, not against it.
Your own controls stay in place
Because your body stays in charge of how much is released, it can still regulate itself. That is a real safety advantage over injected growth hormone.
What the evidence says
Sermorelin was previously approved in the United States for a childhood growth condition, and was withdrawn for commercial reasons rather than safety ones. Using it in adults for sleep, recovery and body composition is off-label and not FDA-approved.
What to expect
- Weeks 1 to 4
Sleep quality is usually the first thing people notice.
- Weeks 4 to 12
Recovery between training sessions and daytime energy tend to follow.
- Months 3 to 6
Changes in body composition, where they happen, are gradual. Your physician reviews your bloodwork and decides whether continuing makes sense.
Protocol
| Standard | Physician-set dose, nightly before sleep |
|---|---|
| Timing | At least 2 hours after your last meal |
| Monitoring | Bloodwork before you start, then at 12 and 24 weeks |
Taken at bedtime on an empty stomach. Eating beforehand, carbohydrate especially, works against the effect you are after.
Is it right for you?
Often a good fit
- Adults with signs of age-related decline in growth hormone, confirmed by a physician
- People whose main complaints are poor sleep and slow recovery
- People who want support for this system with their natural regulation intact
Not a fit
- Anyone with an active cancer diagnosis
- Pregnancy or breastfeeding
- Anyone with an untreated pituitary condition
- Athletes in tested sport, where it is banned